Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074044 | 0.82 | FLT1 (0.52) | NPSR1SMN1; SMN2ALDH1A1FLT1FLT4 | |
| SCHEMBL11276176 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL3335057 | 0.78 | POLB (0.54) | ALDH1A1FLT1FLT4KDRCCR4 | |
| SCHEMBL11265505 | 0.74 | KDM4E (0.55) | SMN1; SMN2ALDH1A1LMNAKDM4ENPC1 | |
| SCHEMBL9852821 | 0.74 | HCRTR1 (0.45) | SMN1; SMN2ALDH1A1KDM4ETHRBTSHR | |
| SCHEMBL11555306 | 0.74 | SMN1; SMN2 (0.65) | NPSR1SMN1; SMN2ALDH1A1FLT1FLT4 | |
| SCHEMBL7226876 | 0.72 | FLT1 (0.49) | SMN1; SMN2ALDH1A1FLT1FLT4KDR | |
| SCHEMBL10867071 | 0.72 | CCR4 (0.41) | SMN1; SMN2ALDH1A1FLT1FLT4KDR | |
| SCHEMBL11156942 | 0.72 | KDM4E (0.52) | SMN1; SMN2ALDH1A1CCR4LMNAMAPT | |
| SCHEMBL6495809 | 0.72 | CA12 (0.50) | ALDH1A1FLT1FLT4KDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |