Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.52 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11275933 | 0.98 | L3MBTL1 (0.56) | L3MBTL1ERCC1ERCC4POLBGFER | |
| Acetic Acid SCHEMBL11272956 | 0.92 | ERCC1 (0.52) | L3MBTL1ERCC1ERCC4POLBGFER | |
| SCHEMBL29709890 | 0.86 | L3MBTL1 (0.60) | L3MBTL1DRD3KCNH2HRH3FFAR1 | |
| SCHEMBL6542369 | 0.86 | L3MBTL1 (0.60) | L3MBTL1DRD3KCNH2HRH3FFAR1 | |
| Bromide SCHEMBL11279741 | 0.86 | L3MBTL1 (0.51) | L3MBTL1ERCC1ERCC4POLBGFER | |
| SCHEMBL7410353 | 0.85 | ERCC1 (0.68) | L3MBTL1ERCC1ERCC4POLBGFER | |
| Hydrochloric Acid SCHEMBL11282579 | 0.79 | MAPT (0.54) | L3MBTL1POLBKMT2AMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11270300 | 0.78 | GAA (0.59) | KMT2ADRD3KCNH2ADRB2ADORA3 | |
| Propionic Acid SCHEMBL11272923 | 0.78 | HCAR2 (0.47) | L3MBTL1ERCC1ERCC4FFAR1CYP1A2 | |
| SCHEMBL6228641 | 0.77 | L3MBTL1 (0.53) | L3MBTL1ERCC1ERCC4POLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327022-A | Heterocyclic alkyl naphthols | STERLING DRUG INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4169108-A | 5(OR 6)-[(Substituted-amino)alkyl]-2,3-naphthalenediols | STERLING DRUG INC. (US) | 1979-09-25 | — | — | US | disclosed |