Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743197 | 0.87 | MAPT (0.55) | CDC25BKMT2APOLBMAPTALDH1A1 | |
| SCHEMBL11305957 | 0.85 | POLB (0.57) | KMT2APOLBMAPTALDH1A1HCAR3 | |
| SCHEMBL11276325 | 0.84 | HCAR3 (0.48) | CDC25BKMT2APOLBMAPTALDH1A1 | |
| SCHEMBL11275613 | 0.83 | HCAR3 (0.49) | CDC25BKMT2APOLBMAPTALDH1A1 | |
| SCHEMBL11266242 | 0.82 | MAPT (0.51) | KMT2APOLBMAPTALDH1A1GAA | |
| SCHEMBL17030649 | 0.81 | ALDH1A1 (0.56) | KMT2APOLBMAPTALDH1A1AKR1C3 | |
| SCHEMBL27510794 | 0.81 | MAPT (0.50) | KMT2APOLBMAPTALDH1A1AKR1C3 | |
| SCHEMBL28322317 | 0.81 | MAPT (0.47) | CDC25BKMT2APOLBMAPTALDH1A1 | |
| Acetic Acid SCHEMBL27680220 | 0.81 | ALDH1A1 (0.47) | CDC25BKMT2APOLBMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27868111 | 0.80 | MAPT (0.49) | KMT2APOLBMAPTALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022017-B1 | DERIVATIVES OF 2-BENZOYL-4-NITRO ANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | PIERRE FABRE S.A. (FR) | 1982-05-05 | — | — | EP | disclosed |
| EP-0022017-A1 | Derivatives of 2-benzoyl-4-nitro anilides, their preparation and their use as medicines | PIERRE FABRE S.A. (FR) | 1981-01-07 | — | — | EP | disclosed |