Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276580 | 1.00 | MME (0.53) | MMESLC7A5PPARGCA2CA1 | |
| SCHEMBL2026268 | 0.88 | PPARG (0.55) | MMESLC7A5PPARGCA2CA1 | |
| SCHEMBL28789648 | 0.86 | PPARG (0.60) | MMEPPARGFOLH1NAALAD2ACE | |
| SCHEMBL28789647 | 0.86 | PPARG (0.60) | MMEPPARGFOLH1NAALAD2ACE | |
| SCHEMBL3923892 | 0.86 | PPARG (0.56) | MMESLC7A5PPARGFOLH1NAALAD2 | |
| SCHEMBL18351661 | 0.86 | PPARG (0.56) | MMESLC7A5PPARGFOLH1NAALAD2 | |
| SCHEMBL3923887 | 0.86 | PPARG (0.56) | MMESLC7A5PPARGFOLH1NAALAD2 | |
| SCHEMBL28981981 | 0.85 | FPR2 (0.55) | MMESLC7A5PPARGCA2CA1 | |
| Phenylalanine SCHEMBL8974614 | 0.83 | SLC7A5 (0.65) | MMESLC7A5PPARGACE | |
| Hydroquinone SCHEMBL28778306 | 0.83 | PPARG (0.56) | MMEPPARGFOLH1NAALAD2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337339-A | Process for preparation of folic acid derivatives | BAKER INSTRUMENTS CORP. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4326060-A | 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID | BAKER INSTRUMENTS CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4314988-A | Folic acid derivatives and process for preparation | BAKER INSTRUMENTS CORP. (US) | 1982-02-09 | — | — | US | disclosed |
| US-4298735-A | Folic acid derivatives | UNION CARBIDE CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |