Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324782 | 0.88 | FPR2 (0.61) | FPR2PPARGMEN1KMT2AMME | |
| SCHEMBL10442661 | 0.87 | FOLH1 (0.48) | FPR2PPARGFOLH1NAALAD2CA1 | |
| SCHEMBL10442660 | 0.87 | FOLH1 (0.48) | FPR2PPARGFOLH1NAALAD2CA1 | |
| SCHEMBL28789648 | 0.86 | PPARG (0.60) | FPR2PPARGFOLH1NAALAD2MME | |
| SCHEMBL18351661 | 0.86 | PPARG (0.56) | PPARGFOLH1NAALAD2SLC7A5MEN1 | |
| SCHEMBL3923892 | 0.86 | PPARG (0.56) | PPARGFOLH1NAALAD2SLC7A5MEN1 | |
| SCHEMBL28789647 | 0.86 | PPARG (0.60) | FPR2PPARGFOLH1NAALAD2MME | |
| SCHEMBL3923887 | 0.86 | PPARG (0.56) | PPARGFOLH1NAALAD2SLC7A5MEN1 | |
| SCHEMBL11276572 | 0.85 | MME (0.53) | PPARGFOLH1NAALAD2CA1CA2 | |
| SCHEMBL11276580 | 0.85 | MME (0.53) | PPARGFOLH1NAALAD2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916234-A | Molecules targeting RAS proteins | 艾琳治疗公司 | 2023-04-04 | — | — | CN | disclosed |