Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.37 |
| ▸ | ARG1 | P05089 | 4/20 | 0.37 |
| ▸ | ARG2 | P78540 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284008 | 0.96 | SMN1; SMN2 (0.41) | DDB1CRBNSMN1; SMN2KMT2ACTSK | |
| Hydrochloric Acid SCHEMBL1809435 | 0.74 | ARG1 (0.48) | GRM2GRM3ARG1ARG2EPHX1 | |
| SCHEMBL8323846 | 0.71 | TSHR (0.47) | SMN1; SMN2KMT2A | |
| SCHEMBL6235555 | 0.69 | CRBN (0.43) | DDB1CRBNSMN1; SMN2HPGD | |
| SCHEMBL8902170 | 0.68 | GRM2 (0.67) | GRM2GRM3GRM6 | |
| SCHEMBL6380145 | 0.68 | FKBP1A (0.47) | SMN1; SMN2 | |
| SCHEMBL30852824 | 0.67 | TSHR (0.45) | DDB1CRBNSMN1; SMN2KMT2A | |
| SCHEMBL11354037 | 0.66 | DDB1 (0.39) | DDB1CRBNKMT2AGRM2GRM3 | |
| SCHEMBL11280639 | 0.66 | SMN1; SMN2 (0.36) | SMN1; SMN2CTSKGRM2GRM3IDO1 | |
| SCHEMBL6271170 | 0.65 | TAAR1 (0.37) | SMN1; SMN2KMT2AEPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315031-A | Thiosubstituted amino acids | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | claimed |
| EP-0001193-B1 | CARBOCYLIC AMINO ACIDS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-10-14 | — | — | EP | claimed |
| US-4315031-A | Thiosubstituted amino acids | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |