Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456973 | 1.00 | EPHX1 (0.49) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL3632496 | 0.88 | EPHX1 (0.50) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL454866 | 0.84 | EPHX1 (0.37) | EPHX1TRPM8TRPA1TRPV1 | |
| SCHEMBL851820 | 0.82 | EPHX1 (0.51) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL15282150 | 0.81 | EPHX1 (0.44) | EPHX1TRPM8TRPA1TRPV1 | |
| Hydrochloric Acid SCHEMBL11492237 | 0.81 | EPHX1 (0.50) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| Bicarbonate SCHEMBL1660899 | 0.81 | EPHX1 (0.50) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL9951257 | 0.80 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL1030886 | 0.80 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 | |
| SCHEMBL3274993 | 0.80 | EPHX1 (0.53) | EPHX1TRPM8TRPA1KCNA5TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 587 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4471114-A2 | TOILET RIM BLOCK OR TOILET CISTERN BLOCK DELIVERING COOLING SENSATIONS | Takasago International Corporation (JP) | 2024-12-04 | — | — | EP | claimed |
| EP-3773445-B1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2024-07-24 | — | — | EP | claimed |
| US-20240041726-A1 | FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION | CHATTEM, INC. | 2024-02-08 | — | — | US | claimed |
| US-11851631-B2 | Household product delivering cooling sensations | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2023-12-26 | — | — | US | claimed |
| EP-3494104-B1 | WARMING SENSATION COMPOUNDS | TAKASAGO PERFUMERY CO LTD (JP) | 2023-11-15 | — | — | EP | claimed |
| CN-116322613-A | Foamable composition, use thereof and method for the production thereof | 查泰姆公司 | 2023-06-23 | — | — | CN | claimed |
| EP-3569671-B1 | METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME | TAKASAGO PERFUMERY CO LTD (JP) | 2022-06-22 | — | — | EP | claimed |
| US-20220110847-A1 | USE OF COOLING MATERIALS FOR THE REDUCTION OR INHIBITION OF SALTINESS IN ORALLY ADMINISTERED, IMBIBED OR INGESTED CONSUMER PRODUCTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2022-04-14 | — | — | US | claimed |
| US-20210179969-A1 | HOUSEHOLD PRODUCT DELIVERING COOLING SENSATIONS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2021-06-17 | — | — | US | claimed |
| EP-2844094-B1 | SMOKING ARTICLE MOUTHPIECE WITH COOLING AGENT INCLUSION COMPLEX | PHILIP MORRIS PRODUCTS SA (CH) | 2021-01-27 | — | — | EP | claimed |
| EP-1973422-A1 | COMPOSITIONS PROVIDING A HEATING SENSATION FOR ORAL OR DERMAL DELIVERY | Cadbury Adams USA LLC (US) | 2008-10-01 | — | — | EP | claimed |
| EP-1958627-A2 | Use of certain menthyl-3-oxocarbonic acid esters as physiological cooling agents | Symrise GmbH & Co. KG (DE) | 2008-08-20 | — | — | EP | claimed |
| US-20080175800-A1 | USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | claimed |
| WO-2007126430-A1 | COMPOSITIONS PROVIDING A HEATING SENSATION FOR ORAL OR DERMAL DELIVERY | CADBURY ADAMS USA LLC (US) | 2007-11-08 | — | — | WO | claimed |
| WO-2006127738-A9 | COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES | CADBURY ADAMS USA LLC (US) | 2007-05-31 | — | — | WO | claimed |
| WO-2006127738-A2 | COMPRESSIBLE CHEWING GUMS FOR DELIVERY OF ACTIVES | CADBURY ADAMS USA LLC (US) | 2006-11-30 | — | — | WO | claimed |
| WO-2006127740-A2 | INDICIA-BEARING PACKAGE FOR DELIVERY SYSTEMS FOR MANAGING RELEASE OF SWEETENERS, SENSATES, FUNCTIONAL INGREDIENTS, FOOD ACIDS AND FLAVORS IN A COMPRESSIBLE GUM SYSTEM | CADBURY ADAMS USA LLC (US) | 2006-11-30 | — | — | WO | claimed |
| US-6838106-B2 | Warming composition for food and drink or for oral care preparation | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-01-04 | — | — | US | claimed |
| US-20030133968-A1 | Refreshing agents, perfumes, sebum-controlling agents, a water-soluble polymer, a polyhydric alcohol, a crosslinking agent, water and a skin care component | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2003-07-17 | — | — | US | claimed |
| EP-1287806-A1 | SHEET-TYPE PACKS | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 2003-03-05 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080175800-A1 | USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES | ECI1, OTC, MDH2 | EPHX1 85/4885TRPM8 528/4885TRPA1 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.