SCHEMBL11276736

SCHEMBL11276736

O=C1CCNC12CCNCC2

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NEK2 P51955 1/20 0.39
CRBN Q96SW2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7613904 0.81 LMNA (0.38) CRBN
Hydrochloric Acid SCHEMBL10802250 0.79 LMNA (0.40)
SCHEMBL22121035 0.77 HTR6 (0.32)
SCHEMBL8640635 0.71 OR51E2 (0.33) CRBN
SCHEMBL2438275 0.71 NEK2 (0.35) NEK2
SCHEMBL16903847 0.70 CYP2D6 (0.36)
SCHEMBL12312682 0.70 GRIN2D (0.36)
SCHEMBL22120967 0.70 HTR6 (0.34)
SCHEMBL23268287 0.70 NEK2 (0.38) NEK2CRBN
SCHEMBL8640104 0.70 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4319030-A Alkylated diaza-spirodecanes HOECHST AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed
US-4191684-A Urea derivatives, their preparation, and their use as light stabilizers HOECHST AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed