Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | IKBKB | O14920 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985765 | 0.99 | ALDH1A1 (0.62) | KDM4EALDH1A1LMNAHTR4MEN1 | |
| SCHEMBL7692996 | 0.92 | HTR4 (0.57) | KDM4EALDH1A1LMNAHTR4POLB | |
| SCHEMBL11275539 | 0.92 | HTR4 (0.57) | KDM4EALDH1A1LMNAHTR4POLB | |
| SCHEMBL11276343 | 0.90 | KDM4E (0.56) | KDM4EALDH1A1LMNAHTR4MEN1 | |
| SCHEMBL11262432 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1LMNAHTR4 | |
| SCHEMBL27986088 | 0.87 | ALDH1A1 (0.60) | KDM4EALDH1A1LMNAPOLBHPGD | |
| SCHEMBL2964718 | 0.84 | IKBKB (0.57) | KDM4EALDH1A1LMNAMEN1POLB | |
| SCHEMBL21347710 | 0.83 | POLB (0.55) | KDM4EALDH1A1MEN1POLBKMT2A | |
| SCHEMBL7531492 | 0.83 | CYP1A2 (0.62) | KDM4EALDH1A1MEN1POLBKMT2A | |
| SCHEMBL13164063 | 0.83 | NPSR1 (0.58) | KDM4EMEN1POLBKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230831-A | Triazine compounds as PI3 kinase and mTOR inhibitors | WYETH LLC | 2014-12-24 | — | — | CN | disclosed |
| EP-0049779-A1 | 3-Aminoindazole derivatives and process for preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-04-21 | — | — | EP | disclosed |