Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | POLM | Q9NP87 | 2/20 | 0.41 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.41 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.41 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283358 | 1.00 | ALOX15 (0.55) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11290492 | 1.00 | ALOX15 (0.55) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11290043 | 1.00 | ALOX15 (0.55) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11284142 | 0.94 | ALOX15 (0.50) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11284326 | 0.93 | ALOX15 (0.49) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11284605 | 0.92 | ALOX15 (0.50) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11284259 | 0.91 | ALOX15 (0.46) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11291256 | 0.91 | ALOX15 (0.47) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11281180 | 0.86 | ALOX15 (0.60) | ALOX15TOP2APOLMPOLKPOLL | |
| SCHEMBL11282406 | 0.86 | ALOX15 (0.60) | ALOX15TOP2APOLMPOLKPOLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |