Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 9/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.38 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.38 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.38 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283358 | 0.94 | ALOX15 (0.55) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11277015 | 0.94 | ALOX15 (0.55) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11290043 | 0.94 | ALOX15 (0.55) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11290492 | 0.94 | ALOX15 (0.55) | ALOX15TOP2ANPC1RAB9AKMT2A | |
| SCHEMBL11284326 | 0.88 | ALOX15 (0.49) | ALOX15ELANETOP2ACYP3A4KMT2A | |
| SCHEMBL11284605 | 0.86 | ALOX15 (0.50) | ALOX15TOP2AALDH1A1NPC1RAB9A | |
| SCHEMBL11284259 | 0.86 | ALOX15 (0.46) | ALOX15ELANETOP2AALDH1A1POLM | |
| SCHEMBL11290593 | 0.86 | ALDH1A1 (0.46) | ELANEALDH1A1LMNACYP3A4HIF1A | |
| SCHEMBL11291256 | 0.85 | ALOX15 (0.47) | ALOX15TOP2APOLMPOLKPOLL | |
| Hydrochloric Acid SCHEMBL11282567 | 0.85 | ADRB2 (0.47) | ELANEALDH1A1LMNACYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |