Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.44 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.44 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.44 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 5/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11284326 | 0.98 | ALOX15 (0.49) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11283358 | 0.91 | ALOX15 (0.55) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11290043 | 0.91 | ALOX15 (0.55) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11277015 | 0.91 | ALOX15 (0.55) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11290492 | 0.91 | ALOX15 (0.55) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11284142 | 0.86 | ALOX15 (0.50) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11288886 | 0.86 | ALOX15 (0.43) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11284605 | 0.83 | ALOX15 (0.50) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL11291256 | 0.82 | ALOX15 (0.47) | ALOX15POLMPOLKPOLLPOLH | |
| SCHEMBL15668298 | 0.82 | ALOX15 (0.52) | ALOX15POLMPOLKPOLLPOLH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |