Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7341046 | 0.94 | IDO1 (0.48) | IDO1LMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL11880603 | 0.92 | SIGMAR1 (0.50) | IDO1LMNASIGMAR1FFAR1HDAC1 | |
| SCHEMBL6743777 | 0.92 | SIGMAR1 (0.50) | IDO1LMNASIGMAR1FFAR1HDAC1 | |
| SCHEMBL6462217 | 0.92 | SIGMAR1 (0.50) | IDO1LMNASIGMAR1FFAR1HDAC1 | |
| SCHEMBL29036387 | 0.92 | SIGMAR1 (0.50) | IDO1LMNASIGMAR1FFAR1HDAC1 | |
| SCHEMBL7107595 | 0.92 | SIGMAR1 (0.50) | IDO1LMNASIGMAR1FFAR1HDAC1 | |
| SCHEMBL6561009 | 0.92 | SIGMAR1 (0.50) | IDO1LMNASIGMAR1FFAR1HDAC1 | |
| SCHEMBL17360726 | 0.89 | IDO1 (0.57) | IDO1LMNASMN1; SMN2NPC1RECQL | |
| SCHEMBL2129084 | 0.87 | TDP1 (0.46) | IDO1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL23928752 | 0.84 | IDO1 (0.57) | IDO1LMNASMN1; SMN2NPC1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766376-B1 | METHOD FOR THE ESTERIFICATION OF P-O COMPONENTS | STRAITMARK HOLDING AG (CH) | 2015-12-30 | — | — | EP | claimed |
| EP-2766376-A1 | METHOD FOR THE ESTERIFICATION OF P-O COMPONENTS | Straitmark Holding AG (CH) | 2014-08-20 | — | — | EP | claimed |
| WO-2013053939-A1 | METHOD FOR THE ESTERIFICATION OF P-O COMPONENTS | STRAITMARK HOLDING AG (CH) | 2013-04-18 | — | — | WO | claimed |
| EP-2581378-A1 | Method for the esterification of P-O components | Straitmark Holding AG (CH) | 2013-04-17 | — | — | EP | claimed |
| CN-115997016-A | Composition comprising nucleic acid nanoparticles having modular functional groups | 西克斯福德生物科学有限公司 | 2023-04-21 | — | — | CN | disclosed |
| EP-2766376-B1 | METHOD FOR THE ESTERIFICATION OF P-O COMPONENTS | STRAITMARK HOLDING AG (CH) | 2015-12-30 | — | — | EP | disclosed |
| EP-2766376-A1 | METHOD FOR THE ESTERIFICATION OF P-O COMPONENTS | Straitmark Holding AG (CH) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013053939-A1 | METHOD FOR THE ESTERIFICATION OF P-O COMPONENTS | STRAITMARK HOLDING AG (CH) | 2013-04-18 | — | — | WO | disclosed |
| EP-2581378-A1 | Method for the esterification of P-O components | Straitmark Holding AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| CN-1230889-A | NAALADase compositions and methods for treating glutamate abnormalities and for producing neuronal activity in animals | GUILFORD PHARM INC (US) | 1999-10-06 | — | — | CN | disclosed |
| CN-1221346-A | Methods of cancer treatment using NAALADase inhibitors | GUILFORD PHARM INC (US) | 1999-06-30 | — | — | CN | disclosed |
| EP-0013382-B1 | PROCESS FOR THE PREPARATION OF M-AMINO-PHENOLS | BASF Aktiengesellschaft (DE) | 1982-12-15 | — | — | EP | disclosed |
| EP-0013382-A1 | Process for the preparation of m-amino-phenols | BASF Aktiengesellschaft (DE) | 1980-07-23 | — | — | EP | disclosed |
| US-4067903-A | Manufacture of arylamines | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-10 | — | — | US | disclosed |