Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11273764 | 0.88 | PLK1 (0.33) | KDM4EMAPTCSNK2A2CSNK2BALDH1A1 | |
| SCHEMBL11283760 | 0.86 | ALDH1A1 (0.36) | KDM4ERAB9AIDO1ALDH1A1HPGD | |
| SCHEMBL11285888 | 0.77 | POLB (0.40) | MAPTRAB9ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL11383593 | 0.70 | NTRK1 (0.39) | KDM4EMAPTMAPK1RAB9ATDP1 | |
| SCHEMBL11284898 | 0.70 | KDM4E (0.40) | KDM4EMAPTMAPK1RAB9ATDP1 | |
| SCHEMBL11274923 | 0.70 | GPR35 (0.43) | KDM4EMAPTMAPK1RAB9ATDP1 | |
| SCHEMBL10482511 | 0.67 | CYSLTR2 (0.32) | ALDH1A1 | |
| SCHEMBL6060851 | 0.65 | KDM4E (0.36) | KDM4EMAPTMAPK1HTTALDH1A1 | |
| SCHEMBL11149383 | 0.65 | AKR1B1 (0.42) | KDM4EMAPTMAPK1RAB9APKM | |
| SCHEMBL3378970 | 0.65 | PRKDC (0.38) | KDM4EMAPTMAPK1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |