Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277624 | 0.88 | KDM4E (0.36) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11283760 | 0.85 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL11273550 | 0.77 | MAPT (0.39) | PLK1MAPT | |
| SCHEMBL6952406 | 0.75 | TNKS (0.55) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11383650 | 0.72 | PLK1 (0.39) | PLK1KDM4EHCRTR1MAPTCASP1 | |
| SCHEMBL11274629 | 0.72 | CYP1A2 (0.40) | PLK1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL11270041 | 0.71 | ALDH1A1 (0.53) | KDM4EALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL7482647 | 0.71 | LCK (0.34) | CSNK2A2CSNK2BCYP1A1CYP1B1CYP1A2 | |
| SCHEMBL11267749 | 0.71 | RAB9A (0.35) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL6957270 | 0.68 | CDK1 (0.38) | ALDH1A1MAPTCSNK2A2CSNK2BGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316904-A | Indolopyrone tetrazoles and carboxamidotetrazoles having antiallergic activity | WARNER-LAMBERT COMPANY | 1982-02-23 | — | — | US | disclosed |