Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287515 | 0.91 | MAPK1 (0.75) | LMNAMAPK1ABCB11MAPTMEN1 | |
| SCHEMBL11263317 | 0.89 | ABCB11 (0.65) | LMNAMAPK1ABCB11MAPTALDH1A1 | |
| SCHEMBL11276195 | 0.88 | LMNA (0.57) | LMNAMAPK1ABCB11MAPTALDH1A1 | |
| SCHEMBL11272380 | 0.86 | LMNA (0.54) | LMNAMAPK1ABCB11MAPTALDH1A1 | |
| SCHEMBL11264433 | 0.84 | LMNA (0.68) | LMNAMAPK1ABCB11MAPTALDH1A1 | |
| SCHEMBL11288224 | 0.84 | MAPT (0.80) | LMNAMAPK1ABCB11MAPTL3MBTL1 | |
| SCHEMBL11271864 | 0.84 | LMNA (0.52) | LMNAMAPK1ABCB11MAPTALDH1A1 | |
| SCHEMBL11265171 | 0.83 | LMNA (0.54) | LMNAMAPK1ABCB11MAPTALDH1A1 | |
| SCHEMBL11267391 | 0.83 | LMNA (0.61) | LMNAMAPK1ABCB11MAPTALDH1A1 | |
| SCHEMBL14769764 | 0.82 | MAPT (0.82) | LMNAMAPK1ABCB11MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |