Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11277852 | 1.00 | GPR183 (0.50) | GPR183NPC1RAB9ATDP1CFD | |
| SCHEMBL11276813 | 0.85 | MEN1 (0.53) | RAB9ACFDGAAMAPT | |
| SCHEMBL11276816 | 0.85 | MEN1 (0.53) | RAB9ACFDGAAMAPT | |
| SCHEMBL11282141 | 0.84 | MAOB (0.58) | NPC1RAB9A | |
| SCHEMBL11282147 | 0.84 | MAOB (0.58) | NPC1RAB9A | |
| SCHEMBL11287920 | 0.82 | CFD (0.41) | CFDGAAMAPT | |
| SCHEMBL11287863 | 0.80 | GAA (0.39) | CFDGAAMAPT | |
| SCHEMBL11282687 | 0.78 | ALDH1A1 (0.61) | NPC1RAB9ATDP1GAAMAPT | |
| SCHEMBL11282683 | 0.78 | ALDH1A1 (0.61) | NPC1RAB9ATDP1GAAMAPT | |
| SCHEMBL11281560 | 0.77 | GBA1 (0.41) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |