Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11276813 | 1.00 | MEN1 (0.53) | MEN1KMT2AARGAAL3MBTL1 | |
| SCHEMBL11287920 | 0.86 | CFD (0.41) | MEN1KMT2AARGAAL3MBTL1 | |
| SCHEMBL11277846 | 0.85 | GPR183 (0.50) | GAAMAPTRAB9ACFD | |
| SCHEMBL11277852 | 0.85 | GPR183 (0.50) | GAAMAPTRAB9ACFD | |
| SCHEMBL11288125 | 0.85 | ALDH1A1 (0.57) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL11288129 | 0.85 | ALDH1A1 (0.57) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL11287863 | 0.84 | GAA (0.39) | MEN1KMT2AARGAAL3MBTL1 | |
| SCHEMBL11282683 | 0.84 | ALDH1A1 (0.61) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL11282687 | 0.84 | ALDH1A1 (0.61) | MEN1KMT2AGAAL3MBTL1POLB | |
| SCHEMBL11282147 | 0.83 | MAOB (0.58) | MEN1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |