Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | KDM6B | O15054 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31355569 | 0.88 | CA2 (0.57) | CA2CA1FOLH1ACEMME | |
| SCHEMBL18619736 | 0.86 | MME (0.56) | CA2CA1FOLH1ACEMME | |
| SCHEMBL2339748 | 0.86 | CA1 (0.58) | CA2CA1FOLH1ACEMME | |
| SCHEMBL2339741 | 0.86 | CA1 (0.58) | CA2CA1FOLH1ACEMME | |
| SCHEMBL8522310 | 0.85 | ACE (0.61) | CA2CA1FOLH1ACEMME | |
| SCHEMBL8257584 | 0.84 | FOLH1 (0.47) | CA2CA1FOLH1ACEMME | |
| SCHEMBL28794655 | 0.83 | CA1 (0.53) | CA2CA1FOLH1ACEMME | |
| SCHEMBL10099834 | 0.83 | ALDH1A1 (0.55) | CA2CA1FOLH1ACEMME | |
| SCHEMBL10099813 | 0.83 | CA1 (0.56) | CA2CA1FOLH1ACEMME | |
| SCHEMBL22473033 | 0.83 | CA2 (0.61) | CA2CA1FOLH1ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339600-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1982-07-13 | — | — | US | claimed |
| US-4339600-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1982-07-13 | — | — | US | disclosed |