Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269817 | 0.82 | CRBN (0.39) | HSD17B10TSHRKDM4EALDH1A1HPGD | |
| SCHEMBL11469819 | 0.74 | GAA (0.42) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL11568230 | 0.72 | TSHR (0.32) | HSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL11459053 | 0.72 | GAA (0.41) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL6666970 | 0.71 | CES2 (0.48) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL11277022 | 0.69 | TSHR (0.46) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL9824029 | 0.69 | ALDH1A1 (0.39) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL5731252 | 0.69 | MGAM (0.46) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL11274787 | 0.68 | CRBN (0.39) | TSHRKDM4EALDH1A1 | |
| SCHEMBL11264137 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329363-A | Substituted mercapto acid amides and their use | MERCK & CO., INC. (US) | 1982-05-11 | — | — | US | disclosed |
| US-4216160-A | IMMUNOREGULANTS FOR CORRECTING AN INBALANCE OF IMMUNE HOMEOSTASIS | MERCK & CO., INC. (US) | 1980-08-05 | — | — | US | disclosed |