Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285612 | 0.87 | LOXL2 (0.46) | LOXL2HTR6HRH3TSHRSIGMAR1 | |
| SCHEMBL11290943 | 0.84 | S1PR5 (0.43) | S1PR5LOXL2HRH3TSHR | |
| SCHEMBL11283349 | 0.81 | HRH3 (0.44) | LOXL2HTR6HRH3SIGMAR1 | |
| SCHEMBL11367098 | 0.80 | HTR6 (0.44) | HTR6HRH3TSHR | |
| Hydrochloric Acid SCHEMBL11231511 | 0.79 | HTR6 (0.43) | LOXL2HTR6HRH3TSHR | |
| SCHEMBL18072429 | 0.77 | LOXL2 (0.54) | LOXL2 | |
| SCHEMBL11386590 | 0.76 | HTR6 (0.41) | LOXL2HTR6HRH3SIGMAR1 | |
| SCHEMBL11726085 | 0.76 | CYP1A2 (0.45) | LOXL2TSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL11240193 | 0.75 | HTR6 (0.40) | LOXL2HTR6HRH3SIGMAR1 | |
| SCHEMBL11234336 | 0.74 | HTR1A (0.44) | HTR6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4313947-A | TREATMENT OF BLOOD DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4216220-A | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-08-05 | — | — | US | disclosed |
| US-4070470-A | BENCYCLOAMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | disclosed |