Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289442 | 0.88 | MAPT (0.52) | LMNAALDH1A1GAAHTTNPSR1 | |
| SCHEMBL3893108 | 0.84 | ALDH1A1 (0.71) | ALDH1A1GAAHTTNPSR1RXFP1 | |
| SCHEMBL11279454 | 0.84 | ALDH1A1 (0.59) | LMNAALDH1A1GAAHTTNPSR1 | |
| SCHEMBL974923 | 0.83 | TRPM8 (0.73) | ALDH1A1GAANPSR1TRPM8SMN1; SMN2 | |
| SCHEMBL276196 | 0.83 | NTRK1 (0.57) | LMNAALDH1A1HTTNPSR1TRPM8 | |
| SCHEMBL9750566 | 0.82 | CDC7 (0.51) | LMNAALDH1A1GAAHTTTRPM8 | |
| SCHEMBL3894571 | 0.82 | ALDH1A1 (0.68) | LMNAALDH1A1GAAHTTNPSR1 | |
| SCHEMBL11288991 | 0.82 | ALDH1A1 (0.57) | LMNAALDH1A1GAAHTTNPSR1 | |
| SCHEMBL19669120 | 0.82 | ALDH1A1 (0.72) | ALDH1A1GAATRPM8SMN1; SMN2DHODH | |
| SCHEMBL28140144 | 0.81 | GAA (0.50) | LMNAALDH1A1GAAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336389-A | 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents | MONSANTO COMPANY (US) | 1982-06-22 | — | — | US | disclosed |