Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127741 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1OPRM1LMNA | |
| SCHEMBL1127830 | 0.91 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1OPRM1LMNA | |
| SCHEMBL1127373 | 0.91 | ALDH1A1 (0.36) | ALDH1A1TSHRMAPK1OPRM1LMNA | |
| SCHEMBL17143544 | 0.84 | — | — | |
| Bicarbonate SCHEMBL3813582 | 0.83 | GABRP (0.38) | ALDH1A1TSHRMAPK1OPRM1 | |
| SCHEMBL16240597 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1OPRM1LMNA | |
| SCHEMBL23028519 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1OPRM1LMNA | |
| SCHEMBL28643674 | 0.79 | OPRM1 (0.55) | ALDH1A1TSHRMAPK1OPRM1LMNA | |
| SCHEMBL28031466 | 0.78 | — | — | |
| SCHEMBL829502 | 0.78 | TRPV1 (0.41) | ALDH1A1TSHRMAPK1OPRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282981-A1 | {F-19} -LABELED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVE (III), USE THEREOF AND METHOD FOR OBTAINING THEM | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141090-A9 | {F-19} -LABELED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVE (III), USE THEREOF AND METHOD FOR OBTAINING THEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-03-25 | — | — | WO | disclosed |
| WO-2009141090-A1 | {F-19} -LABELED L-GLUTAMIC ACID AND L-GLUTAMINE DERIVATIVE (III), USE THEREOF AND METHOD FOR OBTAINING THEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | WO | disclosed |