Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142466 | 0.75 | KDM4E (0.34) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL3457997 | 0.64 | KDM4E (0.38) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL4570765 | 0.61 | KDM4E (0.47) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL870972 | 0.61 | — | — | |
| SCHEMBL15057332 | 0.61 | — | — | |
| SCHEMBL19262448 | 0.60 | KDM4E (0.35) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL2799195 | 0.60 | — | — | |
| SCHEMBL892819 | 0.60 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL13898394 | 0.60 | — | — | |
| SCHEMBL7146308 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |
| US-4358454-A | ANTIULCER AGENT | SCHERING CORPORATION (US) | 1982-11-09 | — | — | US | disclosed |