Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278349 | 1.00 | KMT2A (0.38) | KMT2ATDP1MEN1MAPTKDM4E | |
| SCHEMBL11270617 | 0.89 | MAPT (0.36) | KMT2ATDP1MEN1MAPTKDM4E | |
| SCHEMBL11270613 | 0.89 | MAPT (0.36) | KMT2ATDP1MEN1MAPTKDM4E | |
| SCHEMBL11282400 | 0.85 | MAP1LC3B (0.36) | KMT2AMEN1MAPTKDM4EGAA | |
| SCHEMBL11282397 | 0.85 | MAP1LC3B (0.36) | KMT2AMEN1MAPTKDM4EGAA | |
| SCHEMBL11280438 | 0.77 | KMT2A (0.42) | KMT2ATDP1MEN1MAPTKDM4E | |
| SCHEMBL11280436 | 0.77 | KMT2A (0.42) | KMT2ATDP1MEN1MAPTKDM4E | |
| SCHEMBL11280891 | 0.77 | CYBB (0.39) | KDM4EALDH1A1 | |
| SCHEMBL11277684 | 0.72 | ALDH1A1 (0.49) | KMT2ATDP1MEN1MAPTKDM4E | |
| SCHEMBL11277679 | 0.72 | ALDH1A1 (0.49) | KMT2ATDP1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345935-A | PREEMERGENT AND POSTEMERGENT APPLICATION | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |