Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280438 | 1.00 | KMT2A (0.42) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL11282746 | 0.83 | BCL2A1 (0.52) | KMT2AALDH1A1MEN1MAPTBCL2A1 | |
| SCHEMBL11282741 | 0.83 | BCL2A1 (0.52) | KMT2AALDH1A1MEN1MAPTBCL2A1 | |
| SCHEMBL11278342 | 0.77 | KMT2A (0.38) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL11278349 | 0.77 | KMT2A (0.38) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL11277409 | 0.76 | MEN1 (0.51) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL11277401 | 0.76 | MEN1 (0.51) | KMT2AALDH1A1MEN1TDP1MAPT | |
| SCHEMBL11269792 | 0.75 | NOX4 (0.51) | KMT2AALDH1A1MEN1MAPTBCL2A1 | |
| SCHEMBL11269789 | 0.75 | NOX4 (0.51) | KMT2AALDH1A1MEN1MAPTBCL2A1 | |
| SCHEMBL11274058 | 0.72 | ELANE (0.47) | KMT2AALDH1A1MEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4345936-A | Imidazoles, compositions and herbicidal method | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |
| US-4345935-A | PREEMERGENT AND POSTEMERGENT APPLICATION | ELI LILLY AND COMPANY (US) | 1982-08-24 | — | — | US | disclosed |