Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | CASP7 | P55210 | 4/20 | 0.39 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826128 | 0.90 | UPP1 (0.38) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL17482328 | 0.88 | UPP1 (0.37) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL11354822 | 0.88 | ALDH1A1 (0.40) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL6044950 | 0.82 | MAPT (0.38) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL14279381 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL2884631 | 0.70 | CYP3A4 (0.32) | UPP1MAPTCYP3A4 | |
| SCHEMBL11518089 | 0.70 | HSD17B10 (0.48) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL10474903 | 0.70 | IMPDH2 (0.36) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL14890983 | 0.69 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAHSD17B10UPP1 | |
| SCHEMBL25328460 | 0.69 | FASN (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322304-A | ANTIOXIDANTS | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-30 | — | — | US | disclosed |