Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11092428 | 0.93 | DRD2 (0.52) | DRD2 | |
| SCHEMBL11097949 | 0.92 | DRD2 (0.51) | DRD2 | |
| SCHEMBL11094870 | 0.91 | DRD2 (0.51) | DRD2 | |
| SCHEMBL11094874 | 0.91 | DRD2 (0.61) | DRD2 | |
| SCHEMBL11092436 | 0.88 | MEN1 (0.51) | DRD2SIGMAR1POLBMAPTMEN1 | |
| SCHEMBL11098498 | 0.86 | SIGMAR1 (0.54) | SIGMAR1MAPTMEN1KMT2A | |
| SCHEMBL11094396 | 0.86 | SIGMAR1 (0.46) | SIGMAR1POLBMAPTMEN1KMT2A | |
| SCHEMBL11133855 | 0.85 | ALDH1A1 (0.46) | SIGMAR1POLBMAPTMEN1KMT2A | |
| SCHEMBL11093372 | 0.84 | DRD2 (0.50) | DRD2SIGMAR1MAPTMEN1KMT2A | |
| SCHEMBL11097106 | 0.83 | DRD2 (0.47) | DRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | claimed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |