Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.72 |
| ▸ | CA1 | P00915 | 5/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269522 | 1.00 | CA2 (0.72) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL8671997 | 0.93 | CA2 (0.77) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL4054766 | 0.93 | CA2 (0.77) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL4054764 | 0.93 | CA2 (0.77) | CA2CA1PTPN1CA12CA9 | |
| Aminobenzoic Acid SCHEMBL28815951 | 0.92 | CA2 (0.63) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL15228102 | 0.90 | CA2 (0.61) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL10954969 | 0.89 | MME (0.61) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL7442309 | 0.88 | CA2 (0.71) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL7442291 | 0.88 | CA2 (0.71) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL7363606 | 0.88 | CA2 (0.71) | CA2CA1PTPN1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337339-A | Process for preparation of folic acid derivatives | BAKER INSTRUMENTS CORP. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4326060-A | 6-FORMYLPTERIN, P-AMINOBENZOYL AMINO ACID | BAKER INSTRUMENTS CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |
| US-4314988-A | Folic acid derivatives and process for preparation | BAKER INSTRUMENTS CORP. (US) | 1982-02-09 | — | — | US | disclosed |
| US-4298735-A | Folic acid derivatives | UNION CARBIDE CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |