Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.77 |
| ▸ | CA1 | P00915 | 5/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054766 | 1.00 | CA2 (0.77) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL8671997 | 1.00 | CA2 (0.77) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL7363606 | 0.95 | CA2 (0.71) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL8520566 | 0.94 | PTPN1 (0.72) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL3497780 | 0.94 | PTPN1 (0.72) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL8667639 | 0.94 | CA2 (0.69) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL5793343 | 0.94 | CA2 (0.69) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL3404637 | 0.94 | CA2 (0.69) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL13330076 | 0.93 | CA2 (0.68) | CA2CA1PTPN1CA12CA9 | |
| SCHEMBL13669574 | 0.93 | CA2 (0.70) | CA2CA1PTPN1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114298-B1 | TEMPORARILY STIFFENED MESH PROSTHESES | MEDTRONIC INC (US) | 2022-10-19 | — | — | EP | claimed |
| US-9457129-B2 | Temporarily stiffened mesh prostheses | TYRX, INC. (US) | 2016-10-04 | — | — | US | claimed |
| US-20140046350-A1 | Temporarily Stiffened Mesh Prostheses | TYRX, INC. (US) | 2014-02-13 | — | — | US | claimed |
| US-8636753-B2 | Temporarily stiffened mesh prostheses | TYRX, INC. (US) | 2014-01-28 | — | — | US | claimed |
| EP-2114298-A2 | TEMPORARILY STIFFENED MESH PROSTHESES | TYRX PHARMA INC. (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2009113972-A2 | TEMPORARILY STIFFENED MESH PROSTHESES | TYRX PHARMA, INC. (US) | 2009-09-17 | — | — | WO | claimed |
| US-20070198040-A1 | Temporarily Stiffened Mesh Prostheses | TYRX PHARMA INC. (US) | 2007-08-23 | — | — | US | claimed |