SCHEMBL7442291

SCHEMBL7442291

Nc1ccc(C(=O)N[C@@H](Cc2ccccc2)C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.71
CA1 P00915 4/20 0.71
PTPN1 P18031 2/20 0.70
NPC1 O15118 1/20 0.69
RAB9A P51151 1/20 0.69
ACE P12821 2/20 0.63
MEN1 O00255 2/20 0.58
ALDH1A1 P00352 2/20 0.58
KMT2A Q03164 2/20 0.58
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
GPR132 Q9UNW8 2/20 0.56
ITGB3 P05106 1/20 0.55
ITGA2B P08514 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7442309 1.00 CA2 (0.71) CA2CA1PTPN1NPC1RAB9A
SCHEMBL175867 0.90 CA2 (0.60) CA2CA1PTPN1NPC1RAB9A
SCHEMBL111235 0.89 ACE (0.76) CA2CA1PTPN1ACEMEN1
SCHEMBL111236 0.89 ACE (0.76) CA2CA1PTPN1ACEMEN1
SCHEMBL528464 0.89 ACE (0.76) CA2CA1PTPN1ACEMEN1
SCHEMBL11269522 0.88 CA2 (0.72) CA2CA1PTPN1NPC1RAB9A
SCHEMBL11278740 0.88 CA2 (0.72) CA2CA1PTPN1NPC1RAB9A
SCHEMBL9829430 0.88 NPC1 (0.66) CA2CA1PTPN1NPC1RAB9A
SCHEMBL9829407 0.88 NPC1 (0.66) CA2CA1PTPN1NPC1RAB9A
Hydrochloric Acid SCHEMBL7267838 0.88 CA2 (0.61) CA2CA1PTPN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578566-B1 BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON VERTA RES PRODUCTION COMPANY LTD (RU) 2023-07-19 EP claimed
US-11059860-B2 Biocidal peptide and preparation based thereon VERTA RESEARCH-PRODUCTION COMPANY LTD (RU) 2021-07-13 US claimed
US-20200071358-A1 BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON VERTA RESEARCH-PRODUCTION COMPANY" LTD (RU) 2020-03-05 US claimed
EP-3578566-B1 BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON VERTA RES PRODUCTION COMPANY LTD (RU) 2023-07-19 EP disclosed
CN-110650970-B Antibacterial peptide and medicine thereof 长春艾迪尔医用科技发展有限公司 2023-06-02 CN disclosed
US-11059860-B2 Biocidal peptide and preparation based thereon VERTA RESEARCH-PRODUCTION COMPANY LTD (RU) 2021-07-13 US disclosed
US-20200071358-A1 BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON VERTA RESEARCH-PRODUCTION COMPANY" LTD (RU) 2020-03-05 US disclosed
WO-2018143840-A1 BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON Общество с ограниченной ответственностью "Научно-производственная фирма ВЕРТА" 2018-08-09 WO disclosed
EP-0628559-B1 Pyrimidine compounds and their use as pharmaceuticals BEIERSDORF LILLY GMBH (DE) 2002-04-03 EP disclosed
US-5602137-A Pyrimidine compounds and their use as pharmaceuticals BEIERSDORF-LILLY GMBH (DE) 1997-02-11 US disclosed
US-5602136-A Pyrimidine compounds and their use as pharmaceuticals BEIERSDORF-LILLY GMBH (DE) 1997-02-11 US disclosed
US-5571813-A Fused pyrimidine compounds and their use as pharmaceuticals BEIERSDORF-LILLY GMBH (DE) 1996-11-05 US disclosed
EP-0628559-A1 Pyrimidine compounds and their use as pharmaceuticals Beiersdorf-Lilly GmbH (DE) 1994-12-14 EP disclosed
EP-0178911-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1992-01-22 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 EP disclosed