Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11268200 | 0.78 | MAPK1 (0.58) | MAPK1NPC1RAB9ASMN1; SMN2BRD4 | |
| SCHEMBL11280177 | 0.76 | ADORA2B (0.34) | MAPK1NPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL11279009 | 0.73 | MAPK1 (0.39) | MAPK1SMN1; SMN2PKMBRD4ALDH1A1 | |
| SCHEMBL972162 | 0.70 | CYP19A1 (0.37) | MAPK1SMN1; SMN2PKMHSD17B10TSHR | |
| SCHEMBL9078448 | 0.68 | NR1I2 (0.37) | MAPK1RAB9AHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1847228 | 0.66 | MAPK1 (0.73) | MAPK1NPC1RAB9ASMN1; SMN2BRD4 | |
| SCHEMBL2615574 | 0.66 | MAPK1 (0.55) | MAPK1NPC1RAB9ASMN1; SMN2BRD4 | |
| SCHEMBL2315454 | 0.63 | MAPK1 (0.51) | MAPK1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL15370327 | 0.62 | MAPK1 (1.00) | MAPK1NPC1RAB9ASMN1; SMN2BRD4 | |
| SCHEMBL15761174 | 0.62 | GPR88 (0.41) | PKMADORA2BHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065197-A1 | Substituted 1,3-dioxanes, process for their preparation, herbicides containing them and their use as herbicides | BASF Aktiengesellschaft (DE) | 1982-11-24 | — | — | EP | disclosed |