Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280178 | 0.76 | MAPT (0.35) | MAPK1BRD4TBXAS1ALDH1A1KDM4E | |
| SCHEMBL11268200 | 0.74 | MAPK1 (0.58) | MAPK1BRD4SMN1; SMN2MAPT | |
| SCHEMBL11278995 | 0.73 | MAPK1 (0.46) | MAPK1BRD4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL2041571 | 0.70 | KDM4E (0.42) | MAPK1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7032930 | 0.69 | KCNA4 (0.60) | ALDH1A1KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL28919941 | 0.68 | ALDH1A1 (0.39) | TBXAS1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL11632510 | 0.67 | IDO1 (0.34) | MAPK1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL11636468 | 0.67 | IDO1 (0.34) | MAPK1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL11634894 | 0.67 | IDO1 (0.34) | MAPK1ALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL12619945 | 0.67 | SMN1; SMN2 (0.48) | BRD4TBXAS1HSD11B1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065197-A1 | Substituted 1,3-dioxanes, process for their preparation, herbicides containing them and their use as herbicides | BASF Aktiengesellschaft (DE) | 1982-11-24 | — | — | EP | disclosed |