Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.45 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.45 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.45 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 5/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11279255 | 0.99 | ADRB2 (0.47) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11279245 | 0.99 | ADRB2 (0.47) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11276267 | 0.98 | ALDH1A1 (0.47) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11276263 | 0.97 | ADRB2 (0.47) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11276257 | 0.97 | ADRB2 (0.47) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11281178 | 0.94 | LMNA (0.52) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11278379 | 0.94 | LMNA (0.52) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11281173 | 0.93 | ADRB2 (0.53) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| Hydrochloric Acid SCHEMBL11278354 | 0.93 | ADRB2 (0.53) | ALDH1A1LMNACYP3A4HIF1AADRB2 | |
| SCHEMBL11288392 | 0.90 | LMNA (0.48) | ALDH1A1LMNACYP3A4HIF1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |