Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL11267422 | 0.90 | ALDH1A1 (0.47) | CYP2D6NOTUMTRPA1MPLHRH4 | |
| SCHEMBL11274237 | 0.88 | MPL (0.42) | NOTUMTRPA1KMT2AMPLCOMT | |
| SCHEMBL942110 | 0.88 | TRPA1 (0.50) | TRPA1L3MBTL1KMT2AMPLCOMT | |
| Ammonia Solution, Strong SCHEMBL17272173 | 0.86 | TRPA1 (0.48) | TRPA1L3MBTL1KMT2AMPLCOMT | |
| SCHEMBL17272202 | 0.86 | TRPA1 (0.48) | TRPA1L3MBTL1KMT2AMPLCOMT | |
| SCHEMBL17272460 | 0.86 | TRPA1 (0.48) | TRPA1L3MBTL1KMT2AMPLCOMT | |
| SCHEMBL17272412 | 0.86 | TRPA1 (0.48) | TRPA1L3MBTL1KMT2AMPLCOMT | |
| Ammonia Solution, Strong SCHEMBL17272172 | 0.86 | TRPA1 (0.48) | TRPA1L3MBTL1KMT2AMPLCOMT | |
| Water SCHEMBL11269395 | 0.86 | TRPA1 (0.48) | TRPA1L3MBTL1KMT2AMPLCOMT | |
| SCHEMBL11263530 | 0.84 | MC4R (0.55) | KMT2ASMN1; SMN2LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029990-B1 | BIPHENYLMETHANE DERIVATIVE, METHODS FOR ITS PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-09-08 | — | — | EP | disclosed |
| EP-0029990-A1 | Biphenylmethane derivative, methods for its production and pharmaceutical compositions containing it | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-06-10 | — | — | EP | disclosed |