Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11279299 | 0.99 | ADRB2 (0.55) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| SCHEMBL11288021 | 0.89 | LMNA (0.52) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| SCHEMBL11281630 | 0.89 | LMNA (0.52) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL11281628 | 0.88 | ADRB2 (0.53) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL11288019 | 0.88 | ADRB2 (0.53) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| SCHEMBL11277142 | 0.87 | L3MBTL1 (0.51) | ADRB2ADRB3LMNAHIF1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11281022 | 0.87 | ADRB2 (0.52) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL11277131 | 0.86 | ADRB2 (0.51) | ADRB2ADRB3LMNAHIF1AALDH1A1 | |
| SCHEMBL11281120 | 0.85 | LMNA (0.55) | ADRB2ADRB1ADRB3LMNAHIF1A | |
| Hydrochloric Acid SCHEMBL11281093 | 0.84 | ADRB2 (0.56) | ADRB2ADRB1ADRB3LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |