Styrene

Styrene

SCHEMBL11279338

C=C(C)C(=O)OCCCC.C=C(C)C(=O)OCCCO.C=CC(=O)O.C=CC(=O)OC(CC)CCCCC.C=Cc1ccccc1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.39
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 4/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CTSK P43235 2/20 0.33
CTSL P07711 1/20 0.33
CTSB P07858 1/20 0.33
THRB P10828 2/20 0.32
THRA P10827 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11241736 0.91 TSHR (0.33) TSHRHPGDTDP1POLBAPEX1
Styrene SCHEMBL10612528 0.86 TSHR (0.49) TSHRHPGDTDP1CTSKCTSL
Styrene SCHEMBL2351978 0.86 CTSK (0.39) CTSKCTSLCTSBTHRBTHRA
Styrene SCHEMBL8321010 0.85 TSHR (0.50) TSHRHPGDTDP1POLBAPEX1
Styrene SCHEMBL11253457 0.85 TSHR (0.52) TSHRHPGDTDP1POLBAPEX1
Styrene SCHEMBL9013506 0.84 THRB (0.42) TSHRCTSKCTSLCTSBTHRB
SCHEMBL9186055 0.84 TSHR (0.54) TSHRHPGDTDP1POLBAPEX1
Styrene SCHEMBL11204387 0.83 TSHR (0.48) TSHRHPGDTDP1POLBAPEX1
Styrene SCHEMBL8763825 0.83 TSHR (0.52) TSHRHPGDTDP1POLBAPEX1
Styrene SCHEMBL5400068 0.83 TSHR (0.51) TSHRHPGDTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0051400-A2 Polymeric stabilizer, stable dispersions prepared therefrom and paint compositions comprising such dispersions FORD MOTOR COMPANY LIMITED (GB) 1982-05-12 EP disclosed