Styrene

Styrene

SCHEMBL2351978

C=C(C)C(=O)OC.C=CC(=O)OC(CC)CCCCC.C=Cc1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 7/20 0.39
CTSL P07711 2/20 0.39
CTSB P07858 2/20 0.39
THRB P10828 2/20 0.36
THRA P10827 1/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
CNR2 P34972 1/20 0.36
ALDH1A1 P00352 1/20 0.34
CTSH P09668 1/20 0.33
DAGLA Q9Y4D2 1/20 0.33
PPARG P37231 1/20 0.33
EGFR P00533 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL9013506 0.90 THRB (0.42) CTSKCTSLCTSBTHRBTHRA
Styrene SCHEMBL15709264 0.88 CTSK (0.41) CTSKCTSLCTSBTHRBTHRA
Styrene SCHEMBL6709070 0.88 CTSK (0.41) CTSKCTSLCTSBTAS1R3TAS1R1
SCHEMBL5336277 0.88 ALDH1A1 (0.41) CTSKTHRBALDH1A1
Methacrylic Acid SCHEMBL11217872 0.87 TSHR (0.38) CTSKCTSLCTSBTHRBALDH1A1
Styrene SCHEMBL11279338 0.86 TSHR (0.39) CTSKCTSLCTSBTHRBTHRA
Styrene SCHEMBL28549993 0.84 THRB (0.46) THRBTHRATAS1R3TAS1R1CNR2
Styrene SCHEMBL10612528 0.84 TSHR (0.49) CTSKCTSLCTSBTHRBTHRA
SCHEMBL2351974 0.83 CTSK (0.37) CTSKCTSLCTSBTHRBTHRA
SCHEMBL10942385 0.81 EGFR (0.42) CTSKCTSLCTSBTAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2062953-B1 Heat-sensitive adhesive material RICOH CO LTD (JP) 2011-08-17 EP disclosed
US-20090130441-A1 HEAT-SENSITIVE ADHESIVE MATERIAL RICOH COMPANY, LTD (JP) 2009-05-21 US disclosed