Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279443 | 0.83 | ADRB2 (0.45) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| Alcohol SCHEMBL11277403 | 0.78 | KMT2A (0.43) | MAPTKDM4ENPC1HPGDRAB9A | |
| Alcohol SCHEMBL11283473 | 0.72 | KMT2A (0.36) | MAPTTDP1ALDH1A1HPGDKMT2A | |
| Alcohol SCHEMBL11289619 | 0.70 | MAPT (0.44) | MAPTTDP1KDM4ENPC1RAB9A | |
| SCHEMBL11279439 | 0.70 | MAPK1 (0.40) | MAPTTDP1KDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11283928 | 0.69 | KMT2A (0.42) | MAPTNPC1ALDH1A1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11284135 | 0.69 | KMT2A (0.50) | MAPTKDM4ENPC1RAB9AKMT2A | |
| SCHEMBL11277418 | 0.68 | ADRB2 (0.53) | MAPTTDP1KDM4EKMT2AESR1 | |
| SCHEMBL11282274 | 0.68 | KMT2A (0.49) | MAPTKDM4EALDH1A1HPGDKMT2A | |
| Alcohol SCHEMBL11282266 | 0.67 | ESR1 (0.38) | MAPTKDM4ENPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |