Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279439 | 0.88 | MAPK1 (0.40) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11279437 | 0.83 | MAPT (0.40) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Alcohol SCHEMBL11554389 | 0.79 | ADRB2 (0.46) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11277418 | 0.77 | ADRB2 (0.53) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11283933 | 0.72 | ALDH1A1 (0.47) | KMT2AESR1ESR2MAPTNPC1 | |
| SCHEMBL11282523 | 0.72 | ADRB2 (0.37) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11283482 | 0.72 | PMP22 (0.53) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11282144 | 0.72 | ADRB2 (0.57) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Alcohol SCHEMBL11561438 | 0.71 | ADRB2 (0.48) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11282283 | 0.71 | KMT2A (0.48) | KMT2AMEN1ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |