Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11279443 | 0.88 | ADRB2 (0.45) | MAPK1HTTMAPTTDP1ALDH1A1 | |
| SCHEMBL11277421 | 0.77 | PMP22 (0.51) | TDP1KDM4EKMT2AMEN1CYP2D6 | |
| SCHEMBL11277415 | 0.75 | TBXA2R (0.39) | KDM4EKMT2AMEN1CASP1LMNA | |
| SCHEMBL11289621 | 0.71 | TBXA2R (0.39) | HTTTDP1ALDH1A1GAACASP1 | |
| SCHEMBL11282160 | 0.70 | ADRB2 (0.45) | TDP1KMT2ACYP2D6LMNAADRB2 | |
| SCHEMBL11288295 | 0.70 | LMNA (0.51) | MAPTTDP1ALDH1A1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL11284136 | 0.70 | TTR (0.44) | MAPK1HTTMAPTALDH1A1GAA | |
| SCHEMBL11279437 | 0.70 | MAPT (0.40) | MAPK1MAPTTDP1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11282152 | 0.69 | TDP1 (0.46) | TDP1KMT2ACYP2D6LMNAADRB2 | |
| SCHEMBL11283527 | 0.69 | HTT (0.36) | HTTTDP1FFAR1CASP1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |