SCHEMBL11279475

SCHEMBL11279475

N#CC(CCN=C(c1ccccc1)c1ccccc1)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PADI1 Q9ULC6 5/20 0.37
PADI4 Q9UM07 5/20 0.37
PADI2 Q9Y2J8 4/20 0.37
PDE4A P27815 3/20 0.37
PADI3 Q9ULW8 3/20 0.37
PDE4B Q07343 2/20 0.37
PDE4C Q08493 2/20 0.37
PDE4D Q08499 2/20 0.37
PADI6 Q6TGC4 1/20 0.37
CYP2C19 P33261 4/20 0.37
POLB P06746 2/20 0.37
GAA P10253 1/20 0.37
CYP3A4 P08684 2/20 0.35
PARP1 P09874 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11262727 0.82 KMT2A (0.42) GAATSHRALDH1A1SMN1; SMN2
SCHEMBL11264604 0.81 MEN1 (0.43) POLBGAAMAPTTSHRTDP1
SCHEMBL11279203 0.77 ALDH1A1 (0.40) POLBCYP3A4MAPTTSHRHSD17B10
SCHEMBL11315580 0.73 ALDH1A1 (0.42) POLBGAAMAPTTDP1L3MBTL1
SCHEMBL6216589 0.71 GRIK1 (0.48) MAPTTDP1SMN1; SMN2CTSC
SCHEMBL11284120 0.71 CTSC (0.35) CYP2C19POLBGAACYP3A4PARP1
SCHEMBL2263480 0.69 EPHX1 (0.53) POLBL3MBTL1ALDH1A1CYP1A2CTSC
SCHEMBL11333498 0.69 CYP1A2 (0.43) POLBGAAMAPTHSD17B10TDP1
SCHEMBL17028404 0.69 KMT2A (0.53) CYP2C19POLBCYP3A4MAPTRECQL
SCHEMBL11112239 0.68 POLB (0.37) CYP2C19POLBGAACYP3A4PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0047516-A1 Propylamine derivative and process of manufacturing the same TORAY INDUSTRIES, INC. (JP) 1982-03-17 EP disclosed