SCHEMBL11315580

SCHEMBL11315580

CCOC(=O)C(C#N)CCN=C(N)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NPC1 O15118 2/20 0.42
NOS2 P35228 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2B Q13224 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
GAA P10253 1/20 0.40
POLB P06746 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PIN1 Q13526 1/20 0.37
RAB9A P51151 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11264604 0.87 MEN1 (0.43) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL11333498 0.86 CYP1A2 (0.43) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL24366181 0.78 KMT2A (0.54) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL11279203 0.76 ALDH1A1 (0.40) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL11262727 0.75 KMT2A (0.42) ALDH1A1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL1156065 0.74 KMT2A (0.65) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL11279475 0.73 PADI1 (0.37) ALDH1A1MAPTGRIN1GRIN2BSMN1; SMN2
SCHEMBL11315574 0.72 MEN1 (0.42) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL8433707 0.71 MMP8 (0.43) MEN1KMT2ANPC1SMN1; SMN2GAA
SCHEMBL7391243 0.71 L3MBTL1 (0.56) ALDH1A1MEN1KMT2ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0047516-A1 Propylamine derivative and process of manufacturing the same TORAY INDUSTRIES, INC. (JP) 1982-03-17 EP disclosed