Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 2/20 | 0.62 |
| ▸ | RORC | P51449 | 2/20 | 0.62 |
| ▸ | RORB | Q92753 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.44 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128000 | 0.93 | RORA (0.60) | RORARORCRORBHTR2APSEN1 | |
| SCHEMBL1128427 | 0.84 | RORA (0.60) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL13616802 | 0.81 | RORA (0.59) | RORARORCRORBHTR2APSEN1 | |
| SCHEMBL28031068 | 0.81 | RORA (0.56) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL9707169 | 0.81 | HTR2A (0.53) | RORARORCRORBHTR2APSEN1 | |
| SCHEMBL9707179 | 0.81 | HTR2A (0.53) | RORARORCRORBHTR2APSEN1 | |
| SCHEMBL9707123 | 0.81 | HTR2A (0.53) | RORARORCRORBHTR2APSEN1 | |
| SCHEMBL9707121 | 0.81 | HTR2A (0.53) | RORARORCRORBHTR2APSEN1 | |
| SCHEMBL31442520 | 0.78 | RORA (0.53) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL14141614 | 0.77 | RORA (1.00) | RORARORCRORBCNR2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036992-B | Switchable special effect substances | BASF SE | 2014-11-26 | — | — | CN | disclosed |
| US-20140034623-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2014-02-06 | — | — | US | disclosed |
| US-20140034623-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2014-02-06 | — | — | US | disclosed |
| EP-2283021-B1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2014-01-08 | — | — | EP | disclosed |
| EP-2283021-B1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2014-01-08 | — | — | EP | disclosed |
| US-8586745-B2 | Switchable special effect substances | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| US-8586745-B2 | Switchable special effect substances | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| CN-102036992-A | Switchable special effect substances | BASF SE | 2011-04-27 | — | — | CN | disclosed |
| US-20110060113-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2011-03-10 | — | — | US | disclosed |
| US-20110060113-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2011-03-10 | — | — | US | disclosed |
| EP-2283021-A2 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141288-A2 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060113-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | PPARG, PTGER4, NR2E3 | RORA 174/4885RORC 431/4885RORB 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.