Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
| ▸ | RORB | Q92753 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12083618 | 0.93 | KDM4E (0.51) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL13564044 | 0.88 | RORA (0.52) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL12083709 | 0.87 | KDM4E (0.56) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL9707208 | 0.86 | RORA (0.49) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL9707145 | 0.86 | RORA (0.49) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL9707148 | 0.86 | RORA (0.49) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL12083703 | 0.85 | RORC (0.56) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL11812988 | 0.84 | KDM4E (0.47) | RORARORCRORBKDM4EALDH1A1 | |
| SCHEMBL14280396 | 0.84 | RORA (0.62) | RORARORCRORBALDH1A1MAPT | |
| SCHEMBL13564047 | 0.83 | RORA (0.47) | RORARORCRORBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141288-A2 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |