Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 2/20 | 0.56 |
| ▸ | RORC | P51449 | 2/20 | 0.56 |
| ▸ | RORB | Q92753 | 2/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.54 |
| ▸ | CNR2 | P34972 | 10/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31442520 | 0.88 | RORA (0.53) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL1127961 | 0.81 | RORA (0.62) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL1128427 | 0.79 | RORA (0.60) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL1128000 | 0.79 | RORA (0.60) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL11127173 | 0.78 | SIGMAR1 (0.54) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL3339737 | 0.78 | SIGMAR1 (0.54) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL751367 | 0.78 | SIGMAR1 (0.54) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL3823482 | 0.78 | SIGMAR1 (0.54) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL29393803 | 0.78 | SIGMAR1 (0.54) | RORARORCRORBPSEN1PSEN2 | |
| SCHEMBL29779351 | 0.78 | SIGMAR1 (0.54) | RORARORCRORBPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103232457-B | A kind of novel ring kind based on carbazole | GU LI BIOTECHNOLOGY CO., LTD. (CN) | 2015-09-23 | — | — | CN | disclosed |