Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696496 | 0.90 | LSS (0.53) | TDP1LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3791089 | 0.87 | LTA4H (0.59) | KCNA3TDP1LTA4HHTR1BCHRNB2 | |
| SCHEMBL7212160 | 0.87 | LTA4H (0.55) | KCNA3TDP1LTA4HHTR1BCHRNB2 | |
| SCHEMBL31474674 | 0.84 | LTA4H (0.57) | KCNA3TDP1LTA4HALOX5PPARG | |
| SCHEMBL9145902 | 0.84 | LTA4H (0.57) | KCNA3TDP1LTA4HALOX5PPARG | |
| SCHEMBL29173237 | 0.81 | KCNA3 (0.58) | KCNA3TDP1LTA4HHTR1BCHRNB2 | |
| SCHEMBL18174179 | 0.80 | KCNA3 (0.62) | KCNA3TDP1LTA4HHTR1BDRD2 | |
| SCHEMBL22692744 | 0.79 | KCNA3 (0.56) | KCNA3TDP1LTA4HHTR1BCHRNB2 | |
| SCHEMBL17009054 | 0.79 | LMNA (0.53) | KCNA3LTA4HCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6302467 | 0.78 | ALOX5 (0.59) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140034623-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2014-02-06 | — | — | US | disclosed |
| EP-2283021-B1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2014-01-08 | — | — | EP | disclosed |
| US-8586745-B2 | Switchable special effect substances | BASF SE (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20110060113-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2011-03-10 | — | — | US | disclosed |
| EP-2283021-A2 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009141288-A2 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | BASF SE (DE) | 2009-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060113-A1 | SWITCHABLE SPECIAL EFFECT SUBSTANCES | PPARG, PTGER4, NR2E3 | KCNA3 2229/4885TDP1 3584/4885LTA4H 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.