Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 4/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29776941 | 0.86 | NPC1 (0.56) | NPBWR1MCHR1NPC1RAB9AKMT2A | |
| SCHEMBL11277555 | 0.85 | NPBWR1 (0.60) | NPBWR1MCHR1NPC1RAB9AJUN | |
| SCHEMBL11730032 | 0.80 | NPBWR1 (0.52) | NPBWR1MCHR1NPC1RAB9AJUN | |
| SCHEMBL17074612 | 0.79 | RAB9A (0.59) | NPBWR1MCHR1NPC1RAB9AJUN | |
| Norflurazone SCHEMBL10870860 | 0.75 | CYP1A2 (0.64) | NPBWR1MCHR1NPC1RAB9AKMT2A | |
| SCHEMBL17074605 | 0.74 | CNR2 (0.70) | NPBWR1MCHR1NPC1RAB9AKMT2A | |
| Pyrazon SCHEMBL1858918 | 0.73 | RAB9A (0.70) | NPC1RAB9AKMT2AMAPTHPGD | |
| Pyrazon SCHEMBL53824 | 0.73 | RAB9A (0.70) | NPC1RAB9AKMT2AMAPTHPGD | |
| Pyrazon SCHEMBL7584298 | 0.72 | SMN1; SMN2 (0.42) | NPC1RAB9AACHEKMT2AMAPT | |
| SCHEMBL17074607 | 0.72 | CNR2 (0.54) | NPBWR1MCHR1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |