Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 5/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037242 | 0.85 | NPC1 (0.64) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11280245 | 0.85 | NPBWR1 (0.51) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL13219468 | 0.84 | ACHE (0.57) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL4175570 | 0.84 | RAB9A (0.64) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL17074612 | 0.81 | RAB9A (0.59) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11730032 | 0.79 | NPBWR1 (0.52) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11946538 | 0.79 | RAB9A (0.60) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11205040 | 0.78 | KMT2A (0.65) | RAB9ANPC1ALDH1A1HTTPAX8 | |
| SCHEMBL11732428 | 0.78 | RAB9A (0.48) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11735456 | 0.78 | NPC1 (0.55) | NPBWR1MCHR1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366155-A | 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0063413-A1 | 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method | ELI LILLY AND COMPANY (US) | 1982-10-27 | — | — | EP | disclosed |
| US-4002751-A | SLEEP INDUCERS, CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-01-11 | — | — | US | disclosed |