Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | GOT1 | P17174 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL734585 | 0.84 | MEN1 (1.00) | MEN1KMT2AMAPTGOT1SMN1; SMN2 | |
| SCHEMBL11246728 | 0.81 | MEN1 (0.70) | MEN1KMT2APOLBCDK4CCND1 | |
| SCHEMBL30896267 | 0.77 | HTR2A (0.81) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL17518864 | 0.76 | HTR1A (0.69) | MEN1KMT2AALDH1A1CDK4CCND1 | |
| SCHEMBL27191681 | 0.75 | CDK4 (0.66) | KMT2ACDK4CCND1HTR1AADRA2A | |
| SCHEMBL21073587 | 0.75 | HTR2A (0.68) | MEN1KMT2ASMN1; SMN2ALDH1A1CDK4 | |
| SCHEMBL10649896 | 0.74 | HTR2A (0.66) | MEN1KMT2AALDH1A1CDK4CCND1 | |
| SCHEMBL13255471 | 0.74 | HTR1A (0.58) | KMT2ASMN1; SMN2CDK4CCND1HTR1A | |
| SCHEMBL10652655 | 0.73 | KMT2A (0.54) | MEN1KMT2AMAPTCDK4CCND1 | |
| SCHEMBL7507650 | 0.73 | EPHX1 (0.65) | SMN1; SMN2POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350634-A | HYPOTENSIVE AGENTS | SANDOZ LTD. (CH) | 1982-09-21 | — | — | US | disclosed |